Infection and treatment immunizations for successful parasite vaccines

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Infection and treatment immunizations for successful parasite vaccines

Since the advent of techniques for the expression of recombinant peptide antigens, the availability of human vaccines for parasitic diseases has been 'imminent'. Yet vaccines based on recombinant proteins are still largely aspirations, not realities. It is now apparent that vaccine development needs additional knowledge about host protective immune response(s), antigen characteristics, and the ...

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The Vaccines and Medications in Pregnancy Surveillance System (VAMPSS) has been designed to assess systematically the safety of vaccines and medications during pregnancy and is suited ideally to evaluate the gestational safety of seasonal and pandemic influenza vaccine and influenza antivirals. VAMPSS is coordinated by the American Academy of Allergy Asthma and Immunology and includes 2 complim...

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Hepatitis B Vaccines; Efficacy and Necessity of Booster Immunizations

Most hepatitis B (HB) vaccines are based on recombinant major S protein produced and purified from yeast. To decrease the number of vaccinations, several combination vaccines have been developed, and are commonly used for infant [1-3]. These include HB combined with diphtheria, tetanus, acellular pertussis, and inactivated poliovirus vaccine (DTaP–IPV–HB vaccine); combined hepatitis A and HB va...

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Parasite Carbohydrate Vaccines

Vaccination is an efficient means of combating infectious disease burden globally. However, routine vaccines for the world's major human parasitic diseases do not yet exist. Vaccines based on carbohydrate antigens are a viable option for parasite vaccine development, given the proven success of carbohydrate vaccines to combat bacterial infections. We will review the key components of carbohydra...

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Anti-parasite vaccines.

Introduction Many viral and bacterial diseases are now controlled, at least in developed countries, by vaccination; indeed, smallpox has been eradicated from the earth by this strategy. Despite the fact that three-quarters of the global population currently harbour single or multiple parasitic infections, we have at present no effective vaccines against these ancient scourges of mankind. For ma...

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ژورنال

عنوان ژورنال: Trends in Parasitology

سال: 2013

ISSN: 1471-4922

DOI: 10.1016/j.pt.2013.01.003